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A fast, miniaturised in-vitro assay developed for quantification of lipase enzyme activity
The discovery of allosteric modulators is a multi-disciplinary approach, which is time- and cost-intensive. High-throughput screening combined with novel computational tools can reduce these factors. Thus, we developed an enzyme activity assay, which can be included in the drug discovery work-flow s...
Autores principales: | Menden, Ariane, Hall, Davane, Paris, Daniel, Mathura, Venkatarian, Crawford, Fiona, Mullan, Michael, Crynen, Stefan, Ait-Ghezala, Ghania |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6713963/ https://www.ncbi.nlm.nih.gov/pubmed/31414611 http://dx.doi.org/10.1080/14756366.2019.1651312 |
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