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Sequential stimulation with different concentrations of BMP4 promotes the differentiation of human embryonic stem cells into dental epithelium with potential for tooth formation

BACKGROUND: Tooth loss caused by caries or injuries has a negative effect on human health; thus, it is important to develop a reliable method of tooth regeneration. Research on tooth regeneration has mainly focused on mouse pluripotent stem cells, mouse embryonic stem cells, and adult stem cells fro...

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Detalles Bibliográficos
Autores principales: Li, Qian, Zhang, Siqi, Sui, Yi, Fu, Xiaoming, Li, Yan, Wei, Shicheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6714076/
https://www.ncbi.nlm.nih.gov/pubmed/31464646
http://dx.doi.org/10.1186/s13287-019-1378-7