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Sequential stimulation with different concentrations of BMP4 promotes the differentiation of human embryonic stem cells into dental epithelium with potential for tooth formation
BACKGROUND: Tooth loss caused by caries or injuries has a negative effect on human health; thus, it is important to develop a reliable method of tooth regeneration. Research on tooth regeneration has mainly focused on mouse pluripotent stem cells, mouse embryonic stem cells, and adult stem cells fro...
Autores principales: | Li, Qian, Zhang, Siqi, Sui, Yi, Fu, Xiaoming, Li, Yan, Wei, Shicheng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6714076/ https://www.ncbi.nlm.nih.gov/pubmed/31464646 http://dx.doi.org/10.1186/s13287-019-1378-7 |
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