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Preparation and optimization of polymeric micelles as an oral drug delivery system for deferoxamine mesylate: in vitro and ex vivo studies

Deferoxamine mesylate (DFO) is administered as a slow subcutaneous or intravenous infusion due to its poor oral bioavailability and lack of dose proportionality. The aim of the present study was to prepare and optimize polymeric micelles containing DFO, as an oral drug delivery system for increasing...

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Detalles Bibliográficos
Autores principales: Salimi, Anayatollah, Sharif Makhmal Zadeh, Behzad, Kazemi, Moloud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6714110/
https://www.ncbi.nlm.nih.gov/pubmed/31516506
http://dx.doi.org/10.4103/1735-5362.263554