Klotho induces insulin resistance possibly through interference with GLUT4 translocation and activation of Akt, GSK3β, and PFKfβ3 in 3T3-L1 adipocyte cells

Klotho is considered as an anti-aging factor inducing insulin resistance and involved in type 2 diabetes. However, mechanisms by which klotho induces insulin resistance remain to be understood. Thus, in this study, we aimed to evaluate possible interference points of klotho with insulin signaling pa...

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Detalles Bibliográficos
Autores principales: Hasannejad, Mohamad, Samsamshariat, Seyed Ziaaldin, Esmaili, Armita, Jahanian-Najafabadi, Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6714116/
https://www.ncbi.nlm.nih.gov/pubmed/31516514
http://dx.doi.org/10.4103/1735-5362.263627

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6714116/
https://www.ncbi.nlm.nih.gov/pubmed/31516514
http://dx.doi.org/10.4103/1735-5362.263627

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