Enhanced transient expression of an anti-CD52 monoclonal antibody in CHO cells through utilization of miRNA sponge technology

Chinese hamster ovary (CHO) cells are the dominant mammalian host system for the production of recombinant therapeutic proteins. Improving the viable cell density during culture of recombinant CHO cells can greatly affect the production yield. MicroRNAs (miRs) -15a and 16-1 are known as negative reg...

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Detalles Bibliográficos
Autores principales: Pairawan, Morvarid Sadat, Bolhassani, Azam, Rahimpour, Azam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6714117/
https://www.ncbi.nlm.nih.gov/pubmed/31516510
http://dx.doi.org/10.4103/1735-5362.263626

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6714117/
https://www.ncbi.nlm.nih.gov/pubmed/31516510
http://dx.doi.org/10.4103/1735-5362.263626

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