The Akt/FoxO/p27(Kip1) axis contributes to the anti‐proliferation of pentoxifylline in hypertrophic scars
Hypertrophic scars (HS) are characterized by the excessive production and deposition of extracellular matrix (ECM) proteins. Pentoxifylline (PTX), a xanthine derived antioxidant, inhibits the proliferation, inflammation and ECM accumulation of HS. In this study, we aimed to explore the effect of PTX...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6714140/ https://www.ncbi.nlm.nih.gov/pubmed/31270945 http://dx.doi.org/10.1111/jcmm.14498 |