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Metformin mediates induction of miR‐708 to inhibit self‐renewal and chemoresistance of breast cancer stem cells through targeting CD47

Breast cancer stem cells (BCSCs) have been considered responsible for cancer progression, recurrence, metastasis and drug resistance. However, the mechanisms by which cells acquire self‐renewal and chemoresistance properties are remaining largely unclear. Herein, we evaluated the role of miR‐708 and...

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Detalles Bibliográficos
Autores principales: Tan, Weige, Tang, Hailin, Jiang, Xinhua, Ye, Feng, Huang, Lili, Shi, Dingbo, Li, Laisheng, Huang, Xiaojia, Li, Li, Xie, Xiaoming, Xie, Xinhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6714171/
https://www.ncbi.nlm.nih.gov/pubmed/31273952
http://dx.doi.org/10.1111/jcmm.14462