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EIF2A promotes cell survival during paclitaxel treatment in vitro and in vivo

The integrated stress response (ISR) is critical for cancer cell survival during stress stimuli and has been implicated in the resistance to cancer therapeutics, in which the mechanism, however, is poorly understood. Here, we showed that paclitaxel, the major chemotherapy drug for breast cancer, ind...

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Detalles Bibliográficos
Autores principales: Chen, Lin, He, Jiang, Zhou, Jianhua, Xiao, Zhi, Ding, Nianhua, Duan, Yumei, Li, Wenzheng, Sun, Lun‐Quan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6714208/
https://www.ncbi.nlm.nih.gov/pubmed/31211507
http://dx.doi.org/10.1111/jcmm.14469