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Aurora kinase A stabilizes FOXM1 to enhance paclitaxel resistance in triple‐negative breast cancer

Triple‐negative breast cancer (TNBC) has a relatively poor outcome. Acquired chemoresistance is a major clinical challenge for TNBC patients. Previously, we reported that kinase‐dead Aurora kinase A (Aurora‐A) could effectively transactivate the FOXM1 promoter. Here, we demonstrate an additional pat...

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Detalles Bibliográficos
Autores principales: Yang, Na, Wang, Chang, Wang, Jian, Wang, Zifeng, Huang, Di, Yan, Min, Kamran, Muhammad, Liu, Quentin, Xu, BangLao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6714217/
https://www.ncbi.nlm.nih.gov/pubmed/31359594
http://dx.doi.org/10.1111/jcmm.14538