Cucurbitacin B induces neurogenesis in PC12 cells and protects memory in APP/PS1 mice

Cucurbitacin B (CuB) isolated from Cucumis melo by using a PC12 cell bioassay system exhibited significant nerve growth factor (NGF)‐mimic or NGF‐enhancing activity in PC12 and primary neuron cells. It was also demonstrated pro‐neurogenesis effects in ICR and APP/PS1 mice and improved memory deficit...

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Detalles Bibliográficos
Autores principales: Li, Jing, Sun, Kaiyue, Muroi, Makoto, Gao, Lijuan, Chang, Young‐Tae, Osada, Hiroyuki, Xiang, Lan, Qi, Jianhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6714235/
https://www.ncbi.nlm.nih.gov/pubmed/31257716
http://dx.doi.org/10.1111/jcmm.14514

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6714235/
https://www.ncbi.nlm.nih.gov/pubmed/31257716
http://dx.doi.org/10.1111/jcmm.14514

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