Application of Factorial and Doehlert Designs for the Optimization of the Simultaneous Separation and Determination of Antimigraine Drugs in Pharmaceutical Formulations by RP-HPLC-UV

A sensitive, precise, accurate, and specific isocratic reversed-phase high-performance liquid chromatographic (RP-HPLC) method for the simultaneous separation and determination of zolmitriptan, naratriptan, dihydroergotamine, ketotifen, and pizotifen in pharmaceutical formulations has been developed...

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Detalles Bibliográficos
Autores principales: Jebali, Sami, Belgacem, Chaouki, Louhaichi, Mohamed Radhouen, Bahri, Senda, Latrous El Atarche, Latifa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6714324/
https://www.ncbi.nlm.nih.gov/pubmed/31511775
http://dx.doi.org/10.1155/2019/9685750

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6714324/
https://www.ncbi.nlm.nih.gov/pubmed/31511775
http://dx.doi.org/10.1155/2019/9685750

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