Exosomes derived from microRNA-138-5p-overexpressing bone marrow-derived mesenchymal stem cells confer neuroprotection to astrocytes following ischemic stroke via inhibition of LCN2

BACKGROUND: MicroRNAs (miRNAs) are implicated in the progression of ischemic stroke (IS) and bone marrow-derived mesenchymal stem cells (BMSCs)-derived exosomes play a role in IS therapy. Herein we hypothesized that the BMSCs-derived exosomes containing overexpressed miR-138-5p could protect the ast...

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Detalles Bibliográficos
Autores principales: Deng, Yiming, Chen, Duanduan, Gao, Feng, Lv, Hong, Zhang, Guojun, Sun, Xuan, Liu, Lian, Mo, Dapeng, Ma, Ning, Song, Ligang, Huo, Xiaochuan, Yan, Tianyi, Zhang, Jingbo, Miao, Zhongrong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6714399/
https://www.ncbi.nlm.nih.gov/pubmed/31485266
http://dx.doi.org/10.1186/s13036-019-0193-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6714399/
https://www.ncbi.nlm.nih.gov/pubmed/31485266
http://dx.doi.org/10.1186/s13036-019-0193-0

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