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Development of an oncogenic dedifferentiation SOX signature with prognostic significance in hepatocellular carcinoma

BACKGROUND: Gradual loss of terminal differentiation markers and gain of stem cell-like properties is a major hall mark of cancer malignant progression. The stem cell pluripotent transcriptional factor SOX family play critical roles in governing tumor plasticity and lineage specification. This study...

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Detalles Bibliográficos
Autores principales: Li, Mei-Mei, Tang, Yun-Qiang, Gong, Yuan-Feng, Cheng, Wei, Li, Hao-Long, Kong, Fan-En, Zhu, Wen-Jie, Liu, Shan-Shan, Huang, Li, Guan, Xin-Yuan, Ma, Ning-Fang, Liu, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6714407/
https://www.ncbi.nlm.nih.gov/pubmed/31462277
http://dx.doi.org/10.1186/s12885-019-6041-2