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Development of an oncogenic dedifferentiation SOX signature with prognostic significance in hepatocellular carcinoma
BACKGROUND: Gradual loss of terminal differentiation markers and gain of stem cell-like properties is a major hall mark of cancer malignant progression. The stem cell pluripotent transcriptional factor SOX family play critical roles in governing tumor plasticity and lineage specification. This study...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6714407/ https://www.ncbi.nlm.nih.gov/pubmed/31462277 http://dx.doi.org/10.1186/s12885-019-6041-2 |