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Exploring Novel N-Myristoyltransferase Inhibitors: A Molecular Dynamics Simulation Approach

[Image: see text] N-Myristoyltransferase (NMT) is a cytosolic monomeric enzyme involved in the allocation of the myristoyl group to the aminoterminal of glycine in several viral and eukaryotic cellular proteins. NMT has been validated as a potential drug target against kinetoplastid for parasitic pr...

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Detalles Bibliográficos
Autores principales: Khalil, Ruqaiya, Ashraf, Sajda, Khalid, Asaad, Ul-Haq, Zaheer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6714517/
https://www.ncbi.nlm.nih.gov/pubmed/31497683
http://dx.doi.org/10.1021/acsomega.9b00843