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AntimiR-155 Cyclic Peptide–PNA Conjugate: Synthesis, Cellular Uptake, and Biological Activity

[Image: see text] Efficient delivery of nucleic acids into cells still remains a great challenge. Peptide nucleic acids (PNAs) are DNA analogues with a neutral backbone and are synthesized by solid phase peptide chemistry. This allows a straightforward synthetic route to introduce a linear short pep...

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Detalles Bibliográficos
Autores principales: Soudah, Terese, Khawaled, Saleh, Aqeilan, Rami I., Yavin, Eylon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6714607/
https://www.ncbi.nlm.nih.gov/pubmed/31497713
http://dx.doi.org/10.1021/acsomega.9b01697