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Comparative Analysis of Gene Expression in Virulent and Attenuated Strains of Infectious Bronchitis Virus at Subcodon Resolution

Like all coronaviruses, avian infectious bronchitis virus (IBV) possesses a long, single-stranded, positive-sense RNA genome (∼27 kb) and has a complex replication strategy that includes the production of a nested set of subgenomic mRNAs (sgmRNAs). Here, we used whole-transcriptome sequencing (RNASe...

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Detalles Bibliográficos
Autores principales: Dinan, Adam M., Keep, Sarah, Bickerton, Erica, Britton, Paul, Firth, Andrew E., Brierley, Ian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6714804/
https://www.ncbi.nlm.nih.gov/pubmed/31243124
http://dx.doi.org/10.1128/JVI.00714-19