Cargando…

Comparative Analysis of Gene Expression in Virulent and Attenuated Strains of Infectious Bronchitis Virus at Subcodon Resolution

Like all coronaviruses, avian infectious bronchitis virus (IBV) possesses a long, single-stranded, positive-sense RNA genome (∼27 kb) and has a complex replication strategy that includes the production of a nested set of subgenomic mRNAs (sgmRNAs). Here, we used whole-transcriptome sequencing (RNASe...

Descripción completa

Detalles Bibliográficos
Autores principales:	Dinan, Adam M., Keep, Sarah, Bickerton, Erica, Britton, Paul, Firth, Andrew E., Brierley, Ian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2019
Materias:	Genome Replication and Regulation of Viral Gene Expression
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6714804/ https://www.ncbi.nlm.nih.gov/pubmed/31243124 http://dx.doi.org/10.1128/JVI.00714-19

Ejemplares similares

Deletion of the s2m RNA Structure in the Avian Coronavirus Infectious Bronchitis Virus and Human Astrovirus Results in Sequence Insertions
por: Keep, Sarah, et al.
Publicado: (2023)

Transcriptional and Translational Landscape of Equine Torovirus
por: Stewart, Hazel, et al.
Publicado: (2018)

Programmed −2/−1 Ribosomal Frameshifting in Simarteriviruses: an Evolutionarily Conserved Mechanism
por: Li, Yanhua, et al.
Publicado: (2019)

Characterization of Ribosomal Frameshifting in Theiler's Murine Encephalomyelitis Virus
por: Finch, Leanne K., et al.
Publicado: (2015)

Modulation of Stop Codon Read-Through Efficiency and Its Effect on the Replication of Murine Leukemia Virus
por: Csibra, Eszter, et al.
Publicado: (2014)

Role of RNA Domain Structure and Orientation in the Coxsackievirus B3 Virulence Phenotype
por: Phillips, Lydia, et al.
Publicado: (2023)

Identification of a Novel Post-transcriptional Transactivator from the Equine Infectious Anemia Virus
por: Li, Jiwei, et al.
Publicado: (2022)

Establishment of a Virulent Full-Length cDNA Clone for Type I Feline Coronavirus Strain C3663
por: Terada, Yutaka, et al.
Publicado: (2019)

Single-Nucleotide Resolution Mapping of Hepatitis B Virus Promoters in Infected Human Livers and Hepatocellular Carcinoma
por: Altinel, Kübra, et al.
Publicado: (2016)

Truncation of the Cytoplasmic Tail of Equine Infectious Anemia Virus Increases Virion Production by Improving Env Cleavage and Plasma Membrane Localization
por: Wang, Xue-Feng, et al.
Publicado: (2021)

Deletion of the H240R Gene of African Swine Fever Virus Decreases Infectious Progeny Virus Production Due to Aberrant Virion Morphogenesis and Enhances Inflammatory Cytokine Expression in Porcine Macrophages
por: Zhou, Pingping, et al.
Publicado: (2022)

Oligomerization of the Vesicular Stomatitis Virus Phosphoprotein Is Dispensable for mRNA Synthesis but Facilitates RNA Replication
por: Bloyet, Louis-Marie, et al.
Publicado: (2020)

The ADRP domain from a virulent strain of infectious bronchitis virus is not sufficient to confer a pathogenic phenotype to the attenuated Beaudette strain
por: Keep, Sarah, et al.
Publicado: (2018)

Uncoupling of Influenza A Virus Transcription and Replication through Mutation of the Unpaired Adenosine in the Viral RNA Promoter
por: te Velthuis, Aartjan J. W., et al.
Publicado: (2013)

The Human Adenovirus 5 L4 Promoter Is Activated by Cellular Stress Response Protein p53
por: Wright, Jordan, et al.
Publicado: (2013)

Insights into the Complexity and Functionality of Hepatitis C Virus NS5A Phosphorylation
por: Ross-Thriepland, Douglas, et al.
Publicado: (2014)

An Avian Retrovirus Uses Canonical Expression and Processing Mechanisms To Generate Viral MicroRNA
por: Yao, Yongxiu, et al.
Publicado: (2014)

CCCTC-Binding Factor Recruitment to the Early Region of the Human Papillomavirus 18 Genome Regulates Viral Oncogene Expression
por: Paris, Christian, et al.
Publicado: (2015)

The Human Adenovirus Type 5 L4 Promoter Is Negatively Regulated by TFII-I and L4-33K
por: Wright, Jordan, et al.
Publicado: (2015)

Differentiation-Coupled Induction of Human Cytomegalovirus Replication by Union of the Major Enhancer Retinoic Acid, Cyclic AMP, and NF-κB Response Elements
por: Yuan, Jinxiang, et al.
Publicado: (2015)

MicroRNA-Detargeted Mengovirus for Oncolytic Virotherapy
por: Ruiz, Autumn J., et al.
Publicado: (2016)

Polyprotein-Driven Formation of Two Interdependent Sets of Complexes Supporting Hepatitis C Virus Genome Replication
por: Gomes, Rafael G. B., et al.
Publicado: (2016)

A Subset of CD4/CD8 Double-Negative T Cells Expresses HIV Proteins in Patients on Antiretroviral Therapy
por: DeMaster, Laura K., et al.
Publicado: (2016)

Low-Fidelity Polymerases of Alphaviruses Recombine at Higher Rates To Overproduce Defective Interfering Particles
por: Poirier, Enzo Z., et al.
Publicado: (2016)

An A14U Substitution in the 3′ Noncoding Region of the M Segment of Viral RNA Supports Replication of Influenza Virus with an NS1 Deletion by Modulating Alternative Splicing of M Segment mRNAs
por: Zheng, Min, et al.
Publicado: (2015)

Viral Polymerase-Helicase Complexes Regulate Replication Fidelity To Overcome Intracellular Nucleotide Depletion
por: Stapleford, Kenneth A., et al.
Publicado: (2015)

Mutational Disruption of cis-Acting Replication Element 2C in Coxsackievirus B3 Leads to 5′-Terminal Genomic Deletions
por: Smithee, S., et al.
Publicado: (2015)

HIV Provirus Stably Reproduces Parental Latent and Induced Transcription Phenotypes Regardless of the Chromosomal Integration Site
por: Hashemi, Farhad B., et al.
Publicado: (2016)

HCF1 and OCT2 Cooperate with EBNA1 To Enhance OriP-Dependent Transcription and Episome Maintenance of Latent Epstein-Barr Virus
por: Dheekollu, Jayaraju, et al.
Publicado: (2016)

Identification of a Functionally Relevant Adeno-Associated Virus Rep68 Oligomeric Interface
por: Bardelli, Martino, et al.
Publicado: (2016)

Both cis and trans Activities of Foot-and-Mouth Disease Virus 3D Polymerase Are Essential for Viral RNA Replication
por: Herod, Morgan R., et al.
Publicado: (2016)

A Simplified Positive-Sense-RNA Virus Construction Approach That Enhances Analysis Throughput
por: Siridechadilok, Bunpote, et al.
Publicado: (2013)

Human Choline Kinase-α Promotes Hepatitis C Virus RNA Replication through Modulation of Membranous Viral Replication Complex Formation
por: Wong, Mun-Teng, et al.
Publicado: (2016)

Stimulation of the Replication of ICP0-Null Mutant Herpes Simplex Virus 1 and pp71-Deficient Human Cytomegalovirus by Epstein-Barr Virus Tegument Protein BNRF1
por: Lu, Yongxu, et al.
Publicado: (2016)

Alternative Polyadenylation of Human Bocavirus at Its 3′ End Is Regulated by Multiple Elements and Affects Capsid Expression
por: Hao, Sujuan, et al.
Publicado: (2017)

ZIC2 Is Essential for Maintenance of Latency and Is a Target of an Immediate Early Protein during Kaposi's Sarcoma-Associated Herpesvirus Lytic Reactivation
por: Lyu, Yuanzhi, et al.
Publicado: (2017)

The Surface-Exposed PA(51-72)-Loop of the Influenza A Virus Polymerase Is Required for Viral Genome Replication
por: Nilsson-Payant, Benjamin E., et al.
Publicado: (2018)

Copy Number Heterogeneity, Large Origin Tandem Repeats, and Interspecies Recombination in Human Herpesvirus 6A (HHV-6A) and HHV-6B Reference Strains
por: Greninger, Alexander L., et al.
Publicado: (2018)

Epstein-Barr Virus (EBV) Latent Protein EBNA3A Directly Targets and Silences the STK39 Gene in B Cells Infected by EBV
por: Bazot, Quentin, et al.
Publicado: (2018)

A Mechanism for Priming and Realignment during Influenza A Virus Replication
por: Oymans, Judith, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_17gv01ukjfstp5slqi4juoivgh