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Attenuating the emergence of anti-fungal drug resistance by harnessing synthetic lethal interactions in a model organism
Drug resistance is a rapidly emerging concern, thus prompting the development of novel therapeutics or combinatorial therapy. Currently, combinatorial therapy targets are based on knowledge of drug mode of action and/or resistance mechanisms, constraining the number of target proteins. Unbiased geno...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6715234/ https://www.ncbi.nlm.nih.gov/pubmed/31425501 http://dx.doi.org/10.1371/journal.pgen.1008259 |