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Latency reversal agents affect differently the latent reservoir present in distinct CD4(+) T subpopulations

Latency reversal agents (LRAs) have proven to induce HIV-1 transcription in vivo but are ineffective at decreasing the size of the latent reservoir in antiretroviral treated patients. The capacity of the LRAs to perturb the viral reservoir present in distinct subpopulations of cells is currently unk...

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Detalles Bibliográficos
Autores principales: Grau-Expósito, Judith, Luque-Ballesteros, Laura, Navarro, Jordi, Curran, Adrian, Burgos, Joaquin, Ribera, Esteban, Torrella, Ariadna, Planas, Bibiana, Badía, Rosa, Martin-Castillo, Mario, Fernández-Sojo, Jesús, Genescà, Meritxell, Falcó, Vicenç, Buzon, Maria J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6715238/
https://www.ncbi.nlm.nih.gov/pubmed/31425551
http://dx.doi.org/10.1371/journal.ppat.1007991