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Latency reversal agents affect differently the latent reservoir present in distinct CD4(+) T subpopulations
Latency reversal agents (LRAs) have proven to induce HIV-1 transcription in vivo but are ineffective at decreasing the size of the latent reservoir in antiretroviral treated patients. The capacity of the LRAs to perturb the viral reservoir present in distinct subpopulations of cells is currently unk...
Autores principales: | Grau-Expósito, Judith, Luque-Ballesteros, Laura, Navarro, Jordi, Curran, Adrian, Burgos, Joaquin, Ribera, Esteban, Torrella, Ariadna, Planas, Bibiana, Badía, Rosa, Martin-Castillo, Mario, Fernández-Sojo, Jesús, Genescà, Meritxell, Falcó, Vicenç, Buzon, Maria J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6715238/ https://www.ncbi.nlm.nih.gov/pubmed/31425551 http://dx.doi.org/10.1371/journal.ppat.1007991 |
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