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Characterization of Entamoeba histolytica adenosine 5′-phosphosulfate (APS) kinase; validation as a target and provision of leads for the development of new drugs against amoebiasis

BACKGROUND: Amoebiasis, caused by Entamoeba histolytica infection, is a global public health problem. However, available drugs to treat amoebiasis are currently limited, and no effective vaccine exists. Therefore, development of new preventive measures against amoebiasis is urgently needed. METHODOL...

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Detalles Bibliográficos
Autores principales: Mi-ichi, Fumika, Ishikawa, Takeshi, Tam, Vo Kha, Deloer, Sharmina, Hamano, Shinjiro, Hamada, Tsuyoshi, Yoshida, Hiroki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6715247/
https://www.ncbi.nlm.nih.gov/pubmed/31425516
http://dx.doi.org/10.1371/journal.pntd.0007633