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Coupling adaptive molecular evolution to phylodynamics using fitness-dependent birth-death models
Beneficial and deleterious mutations cause the fitness of lineages to vary across a phylogeny and thereby shape its branching structure. While standard phylogenetic models do not allow mutations to feedback and shape trees, birth-death models can account for this feedback by letting the fitness of l...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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eLife Sciences Publications, Ltd
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6715349/ https://www.ncbi.nlm.nih.gov/pubmed/31411558 http://dx.doi.org/10.7554/eLife.45562 |