Rbfox1 up-regulation impairs BDNF-dependent hippocampal LTP by dysregulating TrkB isoform expression levels

Brain-derived neurotrophic factor (BDNF) is a potent modulator of brain synaptic plasticity. Signaling defects caused by dysregulation of its Ntrk2 (TrkB) kinase (TrkB.FL) and truncated receptors (TrkB.T1) have been linked to the pathophysiology of several neurological and neurodegenerative disorder...

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Detalles Bibliográficos
Autores principales: Tomassoni-Ardori, Francesco, Fulgenzi, Gianluca, Becker, Jodi, Barrick, Colleen, Palko, Mary Ellen, Kuhn, Skyler, Koparde, Vishal, Cam, Maggie, Yanpallewar, Sudhirkumar, Oberdoerffer, Shalini, Tessarollo, Lino
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6715404/
https://www.ncbi.nlm.nih.gov/pubmed/31429825
http://dx.doi.org/10.7554/eLife.49673

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6715404/
https://www.ncbi.nlm.nih.gov/pubmed/31429825
http://dx.doi.org/10.7554/eLife.49673

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