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High serum neurofilament light chain normalizes after hematopoietic stem cell transplantation for MS

OBJECTIVE: To evaluate neurofilament light chain (NfL) levels in serum and CSF of patients with aggressive MS pre- and post-treatment with immunoablation followed by autologous hematopoietic stem cell transplantation (IAHSCT) and examine associations with clinical and MRI outcomes. METHODS: Paired s...

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Detalles Bibliográficos
Autores principales: Thebault, Simon, R. Tessier, Daniel, Lee, Hyunwoo, Bowman, Marjorie, Bar-Or, Amit, Arnold, Douglas L., L. Atkins, Harold, Tabard-Cossa, Vincent, Freedman, Mark S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6715458/
https://www.ncbi.nlm.nih.gov/pubmed/31516913
http://dx.doi.org/10.1212/NXI.0000000000000598