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The role of mycophenolate in the treatment of antineutrophil cytoplasmic antibody-associated vasculitis
Mycophenolic acid, the active metabolite for mycophenolate mofetil and mycophenolic sodium, is a strong, noncompetitive, reversible inhibitor of inosine monophosphate dehydrogenase, the key enzyme in de novo synthesis of guanosine nucleotides leading to selective inhibition of lymphocyte proliferati...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Baishideng Publishing Group Inc
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6715575/ https://www.ncbi.nlm.nih.gov/pubmed/31523631 http://dx.doi.org/10.5527/wjn.v8.i4.75 |