Drug-induced Stress Granule Formation Protects Sensory Hair Cells in Mouse Cochlear Explants During Ototoxicity

Stress granules regulate RNA translation during cellular stress, a mechanism that is generally presumed to be protective, since stress granule dysregulation caused by mutation or ageing is associated with neurodegenerative disease. Here, we investigate whether pharmacological manipulation of the str...

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Detalles Bibliográficos
Autores principales: Gonçalves, Ana Cláudia, Towers, Emily R., Haq, Naila, Porco, John A., Pelletier, Jerry, Dawson, Sally J., Gale, Jonathan E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6715625/
https://www.ncbi.nlm.nih.gov/pubmed/31467369
http://dx.doi.org/10.1038/s41598-019-48393-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6715625/
https://www.ncbi.nlm.nih.gov/pubmed/31467369
http://dx.doi.org/10.1038/s41598-019-48393-w

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