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In vitro fusion of single synaptic and dense core vesicles reproduces key physiological properties

Regulated exocytosis of synaptic vesicles is substantially faster than of endocrine dense core vesicles despite similar molecular machineries. The reasons for this difference are unknown and could be due to different regulatory proteins, different spatial arrangements, different vesicle sizes, or ot...

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Detalles Bibliográficos
Autores principales: Kreutzberger, Alex J. B., Kiessling, Volker, Stroupe, Christopher, Liang, Binyong, Preobraschenski, Julia, Ganzella, Marcelo, Kreutzberger, Mark A. B., Nakamoto, Robert, Jahn, Reinhard, Castle, J. David, Tamm, Lukas K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6715626/
https://www.ncbi.nlm.nih.gov/pubmed/31467284
http://dx.doi.org/10.1038/s41467-019-11873-8