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Cardiac MLC2 kinase is localized to the Z-disc and interacts with α-actinin2
Cardiac contractility is enhanced by phosphorylation of myosin light chain 2 (MLC2) by cardiac-specific MLC kinase (cMLCK), located at the neck region of myosin heavy chain. In normal mouse and human hearts, the level of phosphorylation is maintained relatively constant, at around 30–40% of total ML...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6715661/ https://www.ncbi.nlm.nih.gov/pubmed/31467300 http://dx.doi.org/10.1038/s41598-019-48884-w |