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Distinct methylation levels of mature microRNAs in gastrointestinal cancers

The biological significance of micro (mi)RNAs has traditionally been evaluated according to their RNA expression levels based on the assumption that miRNAs recognize and regulate their targets in an unvarying fashion. Here we show that a fraction of mature miRNAs including miR-17-5p, -21-5p, and -20...

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Detalles Bibliográficos
Autores principales: Konno, Masamitsu, Koseki, Jun, Asai, Ayumu, Yamagata, Akira, Shimamura, Teppei, Motooka, Daisuke, Okuzaki, Daisuke, Kawamoto, Koichi, Mizushima, Tsunekazu, Eguchi, Hidetoshi, Takiguchi, Shuji, Satoh, Taroh, Mimori, Koshi, Ochiya, Takahiro, Doki, Yuichiro, Ofusa, Ken, Mori, Masaki, Ishii, Hideshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6715669/
https://www.ncbi.nlm.nih.gov/pubmed/31467274
http://dx.doi.org/10.1038/s41467-019-11826-1