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Fundamental differences in patterns of retinal ageing between primates and mice

Photoreceptors have high metabolic demands and age rapidly, undermining visual function. We base our understanding mainly on ageing mice where elevated inflammation, extracellular deposition, including that of amyloid beta, and rod and cone photoreceptor loss occur, but cones are not lost in ageing...

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Detalles Bibliográficos
Autores principales: Kam, Jaimie Hoh, Weinrich, Tobias W., Shinhmar, Harpreet, Powner, Michael B., Roberts, Nicholas W., Aboelnour, Asmaa, Jeffery, Glen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6715671/
https://www.ncbi.nlm.nih.gov/pubmed/31467395
http://dx.doi.org/10.1038/s41598-019-49121-0