Identification of somatic mutations in single cell DNA-seq using a spatial model of allelic imbalance

Recent advances in single cell technology have enabled dissection of cellular heterogeneity in great detail. However, analysis of single cell DNA sequencing data remains challenging due to bias and artifacts that arise during DNA extraction and whole-genome amplification, including allelic imbalance...

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Detalles Bibliográficos
Autores principales: Luquette, Lovelace J., Bohrson, Craig L., Sherman, Max A., Park, Peter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6715686/
https://www.ncbi.nlm.nih.gov/pubmed/31467286
http://dx.doi.org/10.1038/s41467-019-11857-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6715686/
https://www.ncbi.nlm.nih.gov/pubmed/31467286
http://dx.doi.org/10.1038/s41467-019-11857-8

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