Miltefosine treatment reduces visceral hypersensitivity in a rat model for irritable bowel syndrome via multiple mechanisms

Irritable bowel syndrome (IBS) is a heterogenic, functional gastrointestinal disorder of the gut-brain axis characterized by altered bowel habit and abdominal pain. Preclinical and clinical results suggested that, in part of these patients, pain may result from fungal induced release of mast cell de...

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Detalles Bibliográficos
Autores principales: Botschuijver, Sara, van Diest, Sophie A., van Thiel, Isabelle A. M., Saia, Rafael S., Strik, Anne S., Yu, Zhumei, Maria-Ferreira, Daniele, Welting, Olaf, Keszthelyi, Daniel, Jennings, Gary, Heinsbroek, Sigrid E. M., Elferink, Ronald P. Oude, Schuren, Frank H. J., de Jonge, Wouter J., van den Wijngaard, René M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6715706/
https://www.ncbi.nlm.nih.gov/pubmed/31467355
http://dx.doi.org/10.1038/s41598-019-49096-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6715706/
https://www.ncbi.nlm.nih.gov/pubmed/31467355
http://dx.doi.org/10.1038/s41598-019-49096-y

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