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EGR1 recruits TET1 to shape the brain methylome during development and upon neuronal activity

Life experience can leave lasting marks, such as epigenetic changes, in the brain. How life experience is translated into storable epigenetic information remains largely unknown. With unbiased data-driven approaches, we predicted that Egr1, a transcription factor important for memory formation, play...

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Detalles Bibliográficos
Autores principales: Sun, Zhixiong, Xu, Xiguang, He, Jianlin, Murray, Alexander, Sun, Ming-an, Wei, Xiaoran, Wang, Xia, McCoig, Emmarose, Xie, Evan, Jiang, Xi, Li, Liwu, Zhu, Jinsong, Chen, Jianjun, Morozov, Alexei, Pickrell, Alicia M., Theus, Michelle H., Xie, Hehuang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6715719/
https://www.ncbi.nlm.nih.gov/pubmed/31467272
http://dx.doi.org/10.1038/s41467-019-11905-3