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EGR1 recruits TET1 to shape the brain methylome during development and upon neuronal activity
Life experience can leave lasting marks, such as epigenetic changes, in the brain. How life experience is translated into storable epigenetic information remains largely unknown. With unbiased data-driven approaches, we predicted that Egr1, a transcription factor important for memory formation, play...
Autores principales: | Sun, Zhixiong, Xu, Xiguang, He, Jianlin, Murray, Alexander, Sun, Ming-an, Wei, Xiaoran, Wang, Xia, McCoig, Emmarose, Xie, Evan, Jiang, Xi, Li, Liwu, Zhu, Jinsong, Chen, Jianjun, Morozov, Alexei, Pickrell, Alicia M., Theus, Michelle H., Xie, Hehuang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6715719/ https://www.ncbi.nlm.nih.gov/pubmed/31467272 http://dx.doi.org/10.1038/s41467-019-11905-3 |
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