Impaired mitochondrial calcium efflux contributes to disease progression in models of Alzheimer’s disease

Impairments in neuronal intracellular calcium ((i)Ca(2+)) handling may contribute to Alzheimer’s disease (AD) development. Metabolic dysfunction and progressive neuronal loss are associated with AD progression, and mitochondrial calcium ((m)Ca(2+)) signaling is a key regulator of both of these proce...

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Detalles Bibliográficos
Autores principales: Jadiya, Pooja, Kolmetzky, Devin W., Tomar, Dhanendra, Di Meco, Antonio, Lombardi, Alyssa A., Lambert, Jonathan P., Luongo, Timothy S., Ludtmann, Marthe H., Praticò, Domenico, Elrod, John W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6715724/
https://www.ncbi.nlm.nih.gov/pubmed/31467276
http://dx.doi.org/10.1038/s41467-019-11813-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6715724/
https://www.ncbi.nlm.nih.gov/pubmed/31467276
http://dx.doi.org/10.1038/s41467-019-11813-6

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