A high-resolution map of non-crossover events reveals impacts of genetic diversity on mammalian meiotic recombination

During meiotic recombination, homologue-templated repair of programmed DNA double-strand breaks (DSBs) produces relatively few crossovers and many difficult-to-detect non-crossovers. By intercrossing two diverged mouse subspecies over five generations and deep-sequencing 119 offspring, we detect tho...

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Detalles Bibliográficos
Autores principales: Li, Ran, Bitoun, Emmanuelle, Altemose, Nicolas, Davies, Robert W., Davies, Benjamin, Myers, Simon R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6715734/
https://www.ncbi.nlm.nih.gov/pubmed/31467277
http://dx.doi.org/10.1038/s41467-019-11675-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6715734/
https://www.ncbi.nlm.nih.gov/pubmed/31467277
http://dx.doi.org/10.1038/s41467-019-11675-y

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