Abundant neuroprotective chaperone Lipocalin-type prostaglandin D synthase (L-PGDS) disassembles the Amyloid-β fibrils

Misfolding of Amyloid β (Aβ) peptides leads to the formation of extracellular amyloid plaques. Molecular chaperones can facilitate the refolding or degradation of such misfolded proteins. Here, for the first time, we report the unique ability of Lipocalin-type Prostaglandin D synthase (L-PGDS) prote...

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Detalles Bibliográficos
Autores principales: Kannaian, Bhuvaneswari, Sharma, Bhargy, Phillips, Margaret, Chowdhury, Anup, Manimekalai, Malathy S. S., Adav, Sunil S., Ng, Justin T. Y., Kumar, Ambrish, Lim, Sierin, Mu, Yuguang, Sze, Siu K., Grüber, Gerhard, Pervushin, Konstantin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6715741/
https://www.ncbi.nlm.nih.gov/pubmed/31467325
http://dx.doi.org/10.1038/s41598-019-48819-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6715741/
https://www.ncbi.nlm.nih.gov/pubmed/31467325
http://dx.doi.org/10.1038/s41598-019-48819-5

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