High-fat and high-cholesterol diet decreases phosphorylated inositol-requiring kinase-1 and inhibits autophagy process in rat liver

Precise molecular pathways involved in the progression of non-alcoholic steatohepatitis (NASH) remain to be elucidated. As Mallory–Denk bodies were occasionally observed in the enlarged hepatocytes in NASH model rat (SHRSP5/Dmcr) fed high-fat and high-cholesterol (HFC) diet, we aimed to clarify the...

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Detalles Bibliográficos
Autores principales: Naito, Hisao, Yoshikawa-Bando, Yuki, Yuan, Yuan, Hashimoto, Sayuki, Kitamori, Kazuya, Yatsuya, Hiroshi, Nakajima, Tamie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6715744/
https://www.ncbi.nlm.nih.gov/pubmed/31467308
http://dx.doi.org/10.1038/s41598-019-48973-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6715744/
https://www.ncbi.nlm.nih.gov/pubmed/31467308
http://dx.doi.org/10.1038/s41598-019-48973-w

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