Cargando…

High-fat and high-cholesterol diet decreases phosphorylated inositol-requiring kinase-1 and inhibits autophagy process in rat liver

Precise molecular pathways involved in the progression of non-alcoholic steatohepatitis (NASH) remain to be elucidated. As Mallory–Denk bodies were occasionally observed in the enlarged hepatocytes in NASH model rat (SHRSP5/Dmcr) fed high-fat and high-cholesterol (HFC) diet, we aimed to clarify the...

Descripción completa

Detalles Bibliográficos
Autores principales:	Naito, Hisao, Yoshikawa-Bando, Yuki, Yuan, Yuan, Hashimoto, Sayuki, Kitamori, Kazuya, Yatsuya, Hiroshi, Nakajima, Tamie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6715744/ https://www.ncbi.nlm.nih.gov/pubmed/31467308 http://dx.doi.org/10.1038/s41598-019-48973-w

Ejemplares similares

The antihypertensive agent hydralazine reduced extracellular matrix synthesis and liver fibrosis in nonalcoholic steatohepatitis exacerbated by hypertension
por: Yuan, Yuan, et al.
Publicado: (2020)

Combination of Hypertension Along with a High Fat and Cholesterol Diet Induces Severe Hepatic Inflammation in Rats via a Signaling Network Comprising NF-κB, MAPK, and Nrf2 Pathways
por: Yuan, Yuan, et al.
Publicado: (2017)

Efficacy of Dietary Lipid Control in Healing High-Fat and High-Cholesterol Diet-Induced Fibrotic Steatohepatitis in Rats
por: Tamada, Hazuki, et al.
Publicado: (2016)

Bile acid detoxifying enzymes limit susceptibility to liver fibrosis in female SHRSP5/Dmcr rats fed with a high-fat-cholesterol diet
por: Yetti, Husna, et al.
Publicado: (2018)

Dysregulated Bile Acid Synthesis, Metabolism and Excretion in a High Fat-Cholesterol Diet-Induced Fibrotic Steatohepatitis in Rats
por: Jia, Xiaofang, et al.
Publicado: (2013)

SIMPLE AND RAPID QUANTITATION OF 21 BILE ACIDS IN RAT SERUM AND LIVER BY UPLC-MS-MS: EFFECT OF HIGH FAT DIET ON GLYCINE CONJUGATES OF RAT BILE ACIDS
por: SUZUKI, YUDAI, et al.
Publicado: (2013)

One-Pot Extraction and Quantification Method for Bile Acids in the Rat Liver by Capillary Liquid Chromatography Tandem Mass Spectrometry
por: Asano, Tomomi, et al.
Publicado: (2021)

Differences in Urinary Arsenic Metabolites between Diabetic and Non-Diabetic Subjects in Bangladesh
por: Nizam, Saika, et al.
Publicado: (2013)

INCIDENCE OF YOUNG ONSET INSULIN-REQUIRING DIABETES MELLITUS AMONG 18- TO 30-YEAR-OLDS IN DHAKA, BANGLADESH (1994−2003)
por: NIZAM, SAIKA, et al.
Publicado: (2012)

A High-Fat and High-Cholesterol Diet Induces Cardiac Fibrosis, Vascular Endothelial, and Left Ventricular Diastolic Dysfunction in SHRSP5/Dmcr Rats
por: Watanabe, Shogo, et al.
Publicado: (2018)

Beneficial Effects of Dietary Nitrite on a Model of Nonalcoholic Steatohepatitis Induced by High-Fat/High-Cholesterol Diets in SHRSP5/Dmcr Rats: A Preliminary Study
por: Sonoda, Kunihiro, et al.
Publicado: (2022)

Increased serum anti-CYP2E1 IgG autoantibody levels may be involved in the pathogenesis of occupational trichloroethylene hypersensitivity syndrome: a case–control study
por: Nakajima, Tamie, et al.
Publicado: (2022)

Inhibited inositol monophosphatase and decreased myo‐inositol concentration improve wasting in skeletal muscles
por: Lee, Ji‐Hyung, et al.
Publicado: (2020)

Lithium induces autophagy by inhibiting inositol monophosphatase
por: Sarkar, Sovan, et al.
Publicado: (2005)

Plasticizers May Activate Human Hepatic Peroxisome Proliferator-Activated Receptor α Less Than That of a Mouse but May Activate Constitutive Androstane Receptor in Liver
por: Ito, Yuki, et al.
Publicado: (2012)

PPARα- and DEHP-Induced Cancers
por: Ito, Yuki, et al.
Publicado: (2008)

Differential Response to Trichloroethylene-Induced Hepatosteatosis in Wild-Type and PPARα-Humanized Mice
por: Ramdhan, Doni Hikmat, et al.
Publicado: (2010)

Simple method to detect triclofos and its metabolites in plasma of children by combined use of liquid chromatography tandem-mass spectrometry and gas chromatography-mass spectrometry
por: Sato, Hirotaka, et al.
Publicado: (2019)

Sphingolipids and Inositol Phosphates Regulate the Tau Protein Phosphorylation Status in Humanized Yeast
por: Randez-Gil, Francisca, et al.
Publicado: (2020)

High Maternal Total Cholesterol Is Associated With No-Catch-up Growth in Full-Term SGA Infants: The Japan Environment and Children’s Study
por: Kaneko, Kayo, et al.
Publicado: (2022)

Intracellular cholesterol transport inhibition Impairs autophagy flux by decreasing autophagosome–lysosome fusion
por: Maharjan, Yunash, et al.
Publicado: (2022)

Trichloroethylene and trichloroethanol induce skin sensitization with focal hepatic necrosis in guinea pigs
por: Zhao, Na, et al.
Publicado: (2020)

Di(2-ethylhexyl) phthalate-induced toxicity and peroxisome proliferator-activated receptor alpha: a review
por: Ito, Yuki, et al.
Publicado: (2019)

Decreased high-density lipoprotein cholesterol levels in polyarticular juvenile idiopathic arthritis
por: Marangoni, Roberta Gonçalves, et al.
Publicado: (2011)

Prognostic Value of Decreased High-Density Lipoprotein Cholesterol Levels in Infective Endocarditis
por: Zampino, Rosa, et al.
Publicado: (2022)

Role of Inositols and Inositol Phosphates in Energy Metabolism
por: Chatree, Saimai, et al.
Publicado: (2020)

Exposure reconstruction of trichloroethylene among patients with occupational trichloroethylene hypersensitivity syndrome
por: NAKAJIMA, Tamie, et al.
Publicado: (2018)

Association between Maternal Exposure to di(2-ethylhexyl) Phthalate and Reproductive Hormone Levels in Fetal Blood: The Hokkaido Study on Environment and Children's Health
por: Araki, Atsuko, et al.
Publicado: (2014)

Adsorption of Inositol Phosphate on Hydroxyapatite Powder with High Specific Surface Area
por: Minamisawa, Hirogo, et al.
Publicado: (2022)

Long-Lasting Therapies with High Doses of D-chiro-inositol: The Downside
por: Nordio, Maurizio, et al.
Publicado: (2023)

Application of Inositol Hexaphosphate and Inositol in Dental Medicine: An Overview
por: Druzijanic, Ana, et al.
Publicado: (2023)

Sweet Potato Leaf Feeding Decreases Cholesterol, Oxidative Stress and Thrombosis Formation in Syrian Hamsters with a High-Cholesterol Diet
por: Chang, Hao-Hsiang, et al.
Publicado: (2021)

Multiple Inositol Polyphosphate Phosphatase Compartmentalization Separates Inositol Phosphate Metabolism from Inositol Lipid Signaling
por: Yu, Jia, et al.
Publicado: (2023)

ITPRs/inositol 1,4,5-trisphosphate receptors in autophagy: From enemy to ally
por: Decuypere, Jean-Paul, et al.
Publicado: (2015)

Inositols in Midlife
por: Kalra, Sanjay, et al.
Publicado: (2018)

Inositols in PCOS
por: Kamenov, Zdravko, et al.
Publicado: (2020)

High-Pressure Acceleration of Nanoliter Droplets in the Gas Phase in a Microchannel
por: Kazoe, Yutaka, et al.
Publicado: (2016)

Broad Spectrum Anticancer Activity of Myo-Inositol and Inositol Hexakisphosphate
por: Bizzarri, Mariano, et al.
Publicado: (2016)

Overview of Inositol and Inositol Phosphates on Chemoprevention of Colitis-Induced Carcinogenesis
por: Weinberg, Samuel E., et al.
Publicado: (2020)

Nur77 Decreases Atherosclerosis Progression in apoE(−/−) Mice Fed a High-Fat/High-Cholesterol Diet
por: Hu, Yan-Wei, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_mjdoftjkm3hbd63stca6fo2qba