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A trade-off for covalent and intercalation binding modes: a case study for Copper (II) ions and singly modified DNA nucleoside
Selective binding to nucleic acids and, more generally, to biopolymers, very often requires at a minimum the presence of specific functionalities and precise spatial arrangement. DNA can fold into defined 3D structures upon binding to metal centers and/or lanthanides. Binding efficiency can be boost...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6715747/ https://www.ncbi.nlm.nih.gov/pubmed/31467417 http://dx.doi.org/10.1038/s41598-019-48935-2 |