Cargando…

A trade-off for covalent and intercalation binding modes: a case study for Copper (II) ions and singly modified DNA nucleoside

Selective binding to nucleic acids and, more generally, to biopolymers, very often requires at a minimum the presence of specific functionalities and precise spatial arrangement. DNA can fold into defined 3D structures upon binding to metal centers and/or lanthanides. Binding efficiency can be boost...

Descripción completa

Detalles Bibliográficos
Autores principales: Mouesca, Jean-Marie, Ahouari, Hania, Dantu, Sarath Chandra, Sicoli, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6715747/
https://www.ncbi.nlm.nih.gov/pubmed/31467417
http://dx.doi.org/10.1038/s41598-019-48935-2