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Novel computational model of gastrula morphogenesis to identify spatial discriminator genes by self-organizing map (SOM) clustering

Deciphering the key mechanisms of morphogenesis during embryonic development is crucial to understanding the guiding principles of the body plan and promote applications in biomedical research fields. Although several computational tissue reconstruction methods using cellular gene expression data ha...

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Detalles Bibliográficos
Autores principales: Mori, Tomoya, Takaoka, Haruka, Yamane, Junko, Alev, Cantas, Fujibuchi, Wataru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6715814/
https://www.ncbi.nlm.nih.gov/pubmed/31467377
http://dx.doi.org/10.1038/s41598-019-49031-1