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Novel computational model of gastrula morphogenesis to identify spatial discriminator genes by self-organizing map (SOM) clustering
Deciphering the key mechanisms of morphogenesis during embryonic development is crucial to understanding the guiding principles of the body plan and promote applications in biomedical research fields. Although several computational tissue reconstruction methods using cellular gene expression data ha...
Autores principales: | Mori, Tomoya, Takaoka, Haruka, Yamane, Junko, Alev, Cantas, Fujibuchi, Wataru |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6715814/ https://www.ncbi.nlm.nih.gov/pubmed/31467377 http://dx.doi.org/10.1038/s41598-019-49031-1 |
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