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Nuclear Factor-kappaB Gates Na(v)1.7 Channels in DRG Neurons via Protein-Protein Interaction
It is well known that nuclear factor-kappaB (NF-κB) regulates neuronal structures and functions by nuclear transcription. Here, we showed that phospho-p65 (p-p65), an active form of NF-κB subunit, reversibly interacted with Na(v)1.7 channels in the membrane of dorsal root ganglion (DRG) neurons of r...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6715905/ https://www.ncbi.nlm.nih.gov/pubmed/31446225 http://dx.doi.org/10.1016/j.isci.2019.08.017 |