Cargando…

Nuclear Factor-kappaB Gates Na(v)1.7 Channels in DRG Neurons via Protein-Protein Interaction

It is well known that nuclear factor-kappaB (NF-κB) regulates neuronal structures and functions by nuclear transcription. Here, we showed that phospho-p65 (p-p65), an active form of NF-κB subunit, reversibly interacted with Na(v)1.7 channels in the membrane of dorsal root ganglion (DRG) neurons of r...

Descripción completa

Detalles Bibliográficos
Autores principales: Xie, Man-Xiu, Zhang, Xiao-Long, Xu, Jing, Zeng, Wei-An, Li, Dai, Xu, Ting, Pang, Rui-Ping, Ma, Ke, Liu, Xian-Guo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6715905/
https://www.ncbi.nlm.nih.gov/pubmed/31446225
http://dx.doi.org/10.1016/j.isci.2019.08.017