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Nuclear Factor-kappaB Gates Na(v)1.7 Channels in DRG Neurons via Protein-Protein Interaction
It is well known that nuclear factor-kappaB (NF-κB) regulates neuronal structures and functions by nuclear transcription. Here, we showed that phospho-p65 (p-p65), an active form of NF-κB subunit, reversibly interacted with Na(v)1.7 channels in the membrane of dorsal root ganglion (DRG) neurons of r...
Autores principales: | Xie, Man-Xiu, Zhang, Xiao-Long, Xu, Jing, Zeng, Wei-An, Li, Dai, Xu, Ting, Pang, Rui-Ping, Ma, Ke, Liu, Xian-Guo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6715905/ https://www.ncbi.nlm.nih.gov/pubmed/31446225 http://dx.doi.org/10.1016/j.isci.2019.08.017 |
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