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Incidental induction of secondary bowel disorders in guinea pigs during a batch safety test of veterinary vaccines

Veterinary vaccines are subjected to a safety testing using laboratory animals via intraperitoneal injection per batch. From April 2010 to March 2011, 7 guinea pigs in 4 batch tests exhibited unrecoverable weight loss and/or were found dead. Six guinea pigs had developed intussusception, whereas ano...

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Detalles Bibliográficos
Autores principales: AIHARA, Naoyuki, OCHIAI, Mariko, HORIUCHI, Noriyuki, YAMAMOTO, Atsushi, SUDO, Kasumi, ISHIKAWA, Yoko, OISHI, Koji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Veterinary Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6715910/
https://www.ncbi.nlm.nih.gov/pubmed/31270308
http://dx.doi.org/10.1292/jvms.19-0058