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Knockdown of KCNQ1OT1 Suppresses Cell Invasion and Sensitizes Osteosarcoma Cells to CDDP by Upregulating DNMT1-Mediated Kcnq1 Expression

Osteosarcoma is a malignant bone tumor, with a high incidence worldwide. The involvement of long non-coding RNAs (lncRNAs) in cancers and their molecular association with the progression of osteosarcoma have been previously discussed. We conducted the present study to examine the effect of lncRNA KC...

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Detalles Bibliográficos
Autores principales: Qi, Xu, Yu, Xiao-Jun, Wang, Xu-Ming, Song, Tie-Nan, Zhang, Jie, Guo, Xin-Zhen, Li, Guo-Jun, Shao, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6716066/
https://www.ncbi.nlm.nih.gov/pubmed/31454677
http://dx.doi.org/10.1016/j.omtn.2019.06.010