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Multi-pathway Protective Effects of MicroRNAs on Human Chondrocytes in an In Vitro Model of Osteoarthritis

Osteoarthritis (OA) is the most common degenerative joint disease. One of the main pathogenic factors of OA is thought to be inflammation. Other factors associated with OA are dysregulation of microRNAs, reduced autophagic activity, oxidative stress, and altered metabolism. microRNAs are small non-c...

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Detalles Bibliográficos
Autores principales: Al-Modawi, Rua Nader, Brinchmann, Jan E., Karlsen, Tommy A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6716067/
https://www.ncbi.nlm.nih.gov/pubmed/31446120
http://dx.doi.org/10.1016/j.omtn.2019.07.011