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Patchy Amphiphilic Dendrimers Bind Adenovirus and Control Its Host Interactions and in Vivo Distribution

[Image: see text] The surface of proteins is heterogeneous with sophisticated but precise hydrophobic and hydrophilic patches, which is essential for their diverse biological functions. To emulate such distinct surface patterns on macromolecules, we used rigid spherical synthetic dendrimers (polyphe...

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Detalles Bibliográficos
Autores principales: Wu, Yuzhou, Li, Longjie, Frank, Larissa, Wagner, Jessica, Andreozzi, Patrizia, Hammer, Brenton, D’Alicarnasso, Marco, Pelliccia, Maria, Liu, Weina, Chakrabortty, Sabyasachi, Krol, Silke, Simon, Johanna, Landfester, Katharina, Kuan, Seah Ling, Stellacci, Francesco, Müllen, Klaus, Kreppel, Florian, Weil, Tanja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6716120/
https://www.ncbi.nlm.nih.gov/pubmed/31322856
http://dx.doi.org/10.1021/acsnano.9b01484