Enhancement of the Anti-Aggregation Activity of a Molecular Chaperone Using a Rationally Designed Post-Translational Modification

[Image: see text] Protein behavior is closely regulated by a plethora of post-translational modifications (PTMs). It is therefore desirable to develop approaches to design rational PTMs to modulate specific protein functions. Here, we report one such method, and we illustrate its successful implemen...

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Detalles Bibliográficos
Autores principales: Lindstedt, Philip R., Aprile, Francesco A., Matos, Maria J., Perni, Michele, Bertoldo, Jean B., Bernardim, Barbara, Peter, Quentin, Jiménez-Osés, Gonzalo, Knowles, Tuomas P. J., Dobson, Christopher M., Corzana, Francisco, Vendruscolo, Michele, Bernardes, Gonçalo J. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6716132/
https://www.ncbi.nlm.nih.gov/pubmed/31482124
http://dx.doi.org/10.1021/acscentsci.9b00467

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6716132/
https://www.ncbi.nlm.nih.gov/pubmed/31482124
http://dx.doi.org/10.1021/acscentsci.9b00467

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